Thionyl Chloride → HCID 178428744, compound

HRID 276524Notes

Reaction equation

HRID 276524 reaction equation
[CH3:1][C:2](O)([CH3:5])[CH2:3][NH2:4].O=S(Cl)Cl.[CH3:11][C:12]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:13]=1[N:21]=[C:22]=[S:23]>>[CH3:11][C:12]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:13]=1[N:21]=[C:22]1[NH:4][CH2:3][C:2]([CH3:5])([CH3:1])[S:23]1

Participants

4

Reactant 3

HCID 24386Thionyl ChlorideHCID 951022-Propanol, 1-amino-2-methyl-HCID 1456212-Methyl-4-nitrophenyl isothiocyanate

Product 1

HCID 178428744HCID 178428744, compound

Procedure

2-Methyl-2-hydroxypropylamine was reacted with SOCl2 followed by 2-methyl-4-nitrophenyl isothiocyanate according to Method C1a to afford 2-(2-methyl-4-nitrophenylimino)-5,5-dimethyl-1,3-thiazolidine. The thiazolidine was reacted with 2-methylprop-2-en-1-yl bromide according to Method D2g to afford 2-(2-methyl-4-nitrophenylimino)-3-(2-methylprop-2-en-1-yl)-5,5-dimethyl-1,3-thiazolidine HBr salt.

Sources & evidence

ORD record
ord-1ec3903d52ed4c79a3bcd1d9e3f67c09
Source dataset
uspto-grants-2002_03
Patent number
US06353006B1

Reaction notes

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