Isopropylamine → NSC 128243

HRID 276536Notes

Reaction equation

[CH:1]([NH2:4])([CH3:3])[CH3:2].[O:5]1[C:7]([CH3:9])([CH3:8])[CH2:6]1>>[CH:1]([NH:4][CH2:6][C:7]([CH3:9])([CH3:8])[OH:5])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 6363Isopropylamine

HCID 11208Isobutylene oxide

Product 1

HCID 97503NSC 128243

Procedure

Isopropylamine was reacted with 1,2-epoxy-2-methylpropane according to Method B5b to give N-isopropyl-N-(2,2-dimethyl-2-hydroxyethyl)amine. N-Isopropyl-N-(2,2-dimethyl-2-hydroxyethyl)amine was reacted with SOCl2 followed by 2-methyl-4-nitrophenyl isothiocyanate according to Method C2f to afford 2-(2-methyl-4-nitrophenylimino)-3-isopropyl-5,5-dimethyl-1,3-thiazolidine.

Sources & evidence

ORD record: ord-2032e836fbb147b68046a9bf71f44b00
Source dataset: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06353006B1

Reaction notes

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