Isobutylamine → HCID 18316285, compound

HRID 276540Notes

Reaction equation

[CH2:1]([NH2:5])[CH:2]([CH3:4])[CH3:3].[O:6]1[C:8]([CH3:10])([CH3:9])[CH2:7]1>>[CH2:1]([NH:5][CH2:7][C:8]([CH3:10])([CH3:9])[OH:6])[CH:2]([CH3:4])[CH3:3]

Participants

Reactant 2

HCID 6558Isobutylamine

HCID 11208Isobutylene oxide

Product 1

HCID 18316285HCID 18316285, compound

Procedure

Isobutylamine was reacted with 1,2-epoxy-2-methylpropane according to Method B5b to give N-isobutyl-N-(2,2-dimethyl-2-hydroxyethyl)amine. N-Isobutyl-N-(2,2-dimethyl-2-hydroxyethyl)amine was reacted with SOCl2 followed by 2,4-dichlorophenyl isothiocyanate according to Method C2f to afford 2-(2,4-1-dichlorophenylimino)-3-isobutyl-5,5-dimethyl-1,3-thiazolidine HCl salt.

Sources & evidence

ORD record: ord-df0c01acdece4d9d903eed0d6ef7cbeb
Source dataset: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06353006B1

Reaction notes

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