2-Methyl-4-nitrophenyl isothiocyanate → HCID 178428743, compound

HRID 276541Notes

Reaction equation

HRID 276541 reaction equation
[Cl-].[CH3:2][C:3]([NH3+:7])([CH3:6])[CH2:4]Cl.[CH3:8][C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[CH:11][C:10]=1[N:18]=[C:19]=[S:20]>>[CH3:8][C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[CH:11][C:10]=1[N:18]=[C:19]1[NH:7][C:3]([CH3:6])([CH3:2])[CH2:4][S:20]1

Participants

3

Reactant 2

HCID 1456212-Methyl-4-nitrophenyl isothiocyanateHCID 865901841,1-Dimethyl-2-chloroethylammonium chloride2×

Product 1

HCID 178428743HCID 178428743, compound

Procedure

1,1-Dimethyl-2-hydroxyamine was converted to 1,1-dimethyl-2-chloroethylammonium chloride according to Method B7a. 2-Methyl-4-nitrophenyl isothiocyanate was reacted with 1,1-dimethyl-2-chloroethylammonium chloride according to Method C1a to give 2-(2-methyl-4-nitrophenylimino)-4,4-dimethyl-1,3-thiazolidine. The thiazolidine was reacted with 2-methylprop-2-en-1-yl bromide according to Method D2g to afford 2-(2-methyl-4-nitrophenylimino)-4,4-dimethyl-3-(2-methylprop-2-en-1-yl)-1,3-thiazolidine HBr salt.

Sources & evidence

ORD record
ord-c56d86f8a875493e8df7279988412b51
Source dataset
uspto-grants-2002_03
Patent number
US06353006B1

Reaction notes

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