HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Iodohexane → N-n-Hexyl-N-(3-carbethoxy-5-ethyl-2-thienyl)-2-methylpropanamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Iodohexane | HCID 12527 | — |
| Edukt | Ethyl 2-amino-5-ethyl-3-thenoate | HCID 78263 | — |
| Edukt | Ethyl 5-ethyl-2-(2-methylpropanoylamino)thiophene-3-carboxylate | HCID 734585 | — |
| Produkt | N-n-Hexyl-N-(3-carbethoxy-5-ethyl-2-thienyl)-2-methylpropanamide | HCID 53840912 | — |
Reaktionsschritte
Ethyl 2-amino-5-ethyl-3-thiophenecarboxylate (Chemische Berichte 99, 94 (1966)) was converted into N-(3-carbethoxy-5-ethyl-2-thienyl)-2-methylpropanamide by the method described in Example 41. Alkylation of the unpurified product with n-hexyl iodide as described in Example 43 gave the title compound as a light yellow oil, b.p. 145°-147° C./0.25 mm. NMR showed that the material was the correct product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04222946 |
| Quelldatensatz | uspto-grants-1980_09 |
| ORD ID | ord-680c2569482649099319afa0ce136218 |
| Quellennotiz | uspto-grants-1980_09 |