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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 276664Generated: October 26, 2026

Chloroacetic Acid → 2-(3-Methyl-4-nitrophenylimino)-3-(phenylmethyl)-1,3-thiazolidin-4-one

https://huagongshe.com/reaction/276664

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetic AcidHCID 300—
ReactantBenzylamineHCID 7504—
Reactant3-Methyl-4-nitrophenyl isothiocyanateHCID 18316341—
Product2-(3-Methyl-4-nitrophenylimino)-3-(phenylmethyl)-1,3-thiazolidin-4-oneHCID 9967824—

Reaction Steps

3-Methyl-4-nitrophenyl isothiocyanate was reacted with benzylamine followed by chloroacetic acid according to Method C8a to afford 2-(3-methyl-4-nitrophenylimino)-3-(phenylmethyl)-1,3-thiazolidin-4-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06353006B1
Source datasetuspto-grants-2002_03
ORD IDord-72e030d55a744cf28297870071298388
Source noteuspto-grants-2002_03