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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 276671Generated: October 26, 2026

Chloroacetic Acid → 2-(2-methyl-4-nitrophenylimino)-3-((1S)-1-cyclohexylethyl)-1,3-thiazolidin-4-one

https://huagongshe.com/reaction/276671

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetic AcidHCID 300—
Reactant2-Methyl-4-nitrophenyl isothiocyanateHCID 145621—
Reactant(S)-(+)-1-CyclohexylethylamineHCID 5325951—
Product2-(2-methyl-4-nitrophenylimino)-3-((1S)-1-cyclohexylethyl)-1,3-thiazolidin-4-oneHCID 22951220—

Reaction Steps

2-Methyl-4-nitrophenyl isothiocyanate was reacted with (1S)-1-amino-1-cyclohexylethane followed by chloroacetic acid according to Method C8a to afford 2-(2-methyl-4-nitrophenylimino)-3-((1S)-1-cyclohexylethyl)-1,3-thiazolidin4-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06353006B1
Source datasetuspto-grants-2002_03
ORD IDord-fc9d4d04f2d24fbf86cc37ff6207be67
Source noteuspto-grants-2002_03