HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloro(phenyl)acetic acid → 5-Phenyl-1,3-thiazolidin4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloro(phenyl)acetic acid | HCID 98950 | — |
| Reactant | 2-Methyl-4-nitrophenyl isothiocyanate | HCID 145621 | — |
| Reactant | (S)-(+)-1-Cyclohexylethylamine | HCID 5325951 | — |
| Product | 5-Phenyl-1,3-thiazolidin4-one | HCID 21439807 | — |
Reaction Steps
2-Methyl-4-nitrophenyl isothiocyanate was reacted with (1S)-1-amino-1-cyclohexylethane followed by α-chloro-α-phenylacetic acid according to Method C8a to afford 2-(2-methyl-4-nitrophenylimino)-3-((]S)-1-cyclohexylethyl)-5-phenyl-1,3-thiazolidin4-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06353006B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-485529848761479b8f33bc6f8022131a |
| Source note | uspto-grants-2002_03 |