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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 276681Generated: October 26, 2026

Chloroacetic Acid → 2-(2-methyl-4-nitrophenylimino)-3-((2S)-2-methyl-1-butyl)-1,3-thiazolidin-4-one

https://huagongshe.com/reaction/276681

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetic AcidHCID 300—
Reactant2-Methyl-4-nitrophenyl isothiocyanateHCID 145621—
Reactant2-Methylbutylamine, (S)-HCID 2724272—
Product2-(2-methyl-4-nitrophenylimino)-3-((2S)-2-methyl-1-butyl)-1,3-thiazolidin-4-oneHCID 59113142—

Reaction Steps

2-Methyl-4-nitrophenyl isothiocyanate was reacted with (2S)-2-methyl-1-butylamine followed by chloroacetic acid according to Method C8a to afford 2-(2-methyl-4-nitrophenylimino)-3-((2S)-2-methyl-1-butyl)-l ,3-thiazolidin4-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06353006B1
Source datasetuspto-grants-2002_03
ORD IDord-c5bcedf078084dbeb9d39d97b7239aeb
Source noteuspto-grants-2002_03