2-Methyl-4-nitrophenyl isothiocyanate → HCID 57013288, compound

HRID 276686Notes

Reaction equation

HRID 276686 reaction equation
C(O[C:4](=[O:15])[C@H:5]([CH2:11][CH:12]([CH3:14])[CH3:13])[NH:6][CH2:7][CH:8]([CH3:10])[CH3:9])C.[CH3:16][C:17]1[CH:22]=[C:21]([N+:23]([O-:25])=[O:24])[CH:20]=[CH:19][C:18]=1[N:26]=[C:27]=[S:28]>>[CH3:16][C:17]1[CH:22]=[C:21]([N+:23]([O-:25])=[O:24])[CH:20]=[CH:19][C:18]=1[N:26]=[C:27]1[N:6]([CH2:7][CH:8]([CH3:9])[CH3:10])[C@@H:5]([CH2:11][CH:12]([CH3:13])[CH3:14])[C:4](=[O:15])[S:28]1

Participants

3

Reactant 2

HCID 1456212-Methyl-4-nitrophenyl isothiocyanateHCID 54344486HCID 54344486, compound

Product 1

HCID 57013288HCID 57013288, compound

Procedure

N-Isobutylleucine ethyl ester was reacted with 2-methyl-4-nitrophenyl isothiocyanate according to Method C11a to afford (4S)-2-(2-methyl-4-nitrophenylimino)-3,4-diisobutyl-1,3-thiazolidin-5-one.

Sources & evidence

ORD record
ord-3b665a08672f4392969c2eee02d12630
Source dataset
uspto-grants-2002_03
Patent number
US06353006B1

Reaction notes

Loading…