HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 533450, compound → HCID 86591128, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 533450 | HCID 533450 | — |
| Reactant | HCID 22951556 | HCID 22951556 | — |
| Reactant | HCID 68440021 | HCID 68440021 | — |
| Product | HCID 86591128 | HCID 86591128 | 36% |
Reaction Steps
The title compound is prepared analogously to the compound of Example 22. N-(Naphthalene-2-carbonyl)-leucine and 1-cyano-2-(1H-indol-3-yl)-ethylamine (CAS 169545-97-5) are reacted by the same procedure as for Naphthalene-2-carboxylic acid [1-(1-cyano-3-methyl-butylcarbamoyl)-3-methyl-butyl]-amide, to give the product in 36% yield after chromatography on silica gel (hexane/ethyl acetate 1/1) (mixture of epimers).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06353017B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-33f75f7503f2430fb11692fda09dbeac |
| Source note | uspto-grants-2002_03 |