反应详情

A solution of 500 g of 4-isopropenyl-3,7-dimethyl-6-octen-1-yn-3-ol in 1.5 liters of n-hexane was hydrogenated at ambient temperature and atmospheric pressure using 25 g of 0.25% Lindlar catalyst. The reaction was sequentially monitored by gas chromatography (PEG20M, 150° C.) and the reaction was terminated when no starting material remained. The catalyst was filtered off and the solvent was removed from the filtrate by distillation under reduced pressure. The residue was distilled in vacuo to obtain 482 g of 4-isopropenyl-3,7-dimethyl-1,6-octadien-3-ol as a fore-running distillate at bp. 55°-59° C./0.4 mm Hg.

1. customwas hydrogenated at ambient temperature
2. customwas sequentially monitored by gas chromatography (PEG20M, 150° C.)
3. customthe reaction was terminated when no starting material
4. filtrationThe catalyst was filtered off
5. customthe solvent was removed from the filtrate by distillation under reduced pressure
6. distillationThe residue was distilled in vacuo