N-bromobutanimide → 2-bromo-5-phenylthiophene

Next, 3.21 g (20 mmol) of the thus synthesized 2-phenylthiophene was dissolved into 20 mL of methanol, and then to this solution was added a solution wherein 3.92 g (22 mmol) of N-bromosuccinimide (Wako Pure Chemicals Industries, Ltd.) was dissolved into 40 mL of methanol, to produce a white precipitation of 2-phenyl-5-bromothiophene immediately. This reaction solution was put into a refrigerator to ensure the production of the precipitation. This precipitation was filtered and then was sufficiently washed with a great deal of a mixture solution of equivalent amounts of water and methanol. The resultant was dried one day and night to obtain a white crystal (2.4 g) of 2-phenyl-5-bromothiophene.

1. customto produce
2. customa white precipitation of 2-phenyl-5-bromothiophene immediately
3. customthe production of the precipitation
4. customThis precipitation
5. filtrationwas filtered
6. washwas sufficiently washed with a great deal of a mixture solution of equivalent amounts of water and methanol
7. customThe resultant was dried one day and night

ORD record

ord-b56225e69065413792dffad8c708c17c

Source dataset

uspto-grants-2002_03

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US06355365B1