4-ethoxymethylene-2-(1)-naphthyl-5(4H)-oxazolone → 4-{4-[(benzylidene-amino)-methyl]-piperidin-1-ylmethylene}-2-naphthalen-1-yl-4H-oxazol-5-one

Participants

Reaction Steps

To a solution of 4-ethoxymethylene-2-naphthalen-1-yl-4H-oxazol-5-one (11.40 g, 43 mmol) in tetrahydrofuran, benzylidene-piperidin-4-ylmethyl-amine (8.60 g, 43 mmol) was added, and the mixture was stirred at room temperature for 24 h. The reaction mixture was concentrated under reduced pressure to yield 4-{4-[(benzylidene-amino)-methyl]-piperidin-1-ylmethylene}-2-naphthalen-1-yl-4H-oxazol-5-one.

Provenance & Evidence