反应详情

0.3 ml of acetic anhydride was added to 1.4 g (4.8 mM) of 2-amino-3,5-dicarbethoxy-4,6-dihydrothieno[3,2-c]pyrrole in 14 ml of triethylorthoformate and refluxed under nitrogen for 1 h. The mixture was then completely evaporated in a rotary evaporator at 80° C. 1.6 g (99%) of crude product were isolated as a viscous oil which is sufficiently pure for further reactions.

1. temperaturerefluxed under nitrogen for 1 h
2. customThe mixture was then completely evaporated in a rotary evaporator at 80° C