反应详情

Hydrolysis of ethyl 4-anilino-1,2,3-triazole-5-carboxylate (9.29 g; 0.04 mole) with 1.25 N sodium hydroxide (200 ml) at 90° C. for 18 hrs. gave the free acid in quantitative yield. Recrystallisation from water containing a minimum of ethanol gave material of mp 149.5-150.5° C. (dec) (lit. mp. 153° C., O. Dimroth Annalen 364 183 [1909]), (Found; C, 52.88; H, 4.14; N, 27.36; C9H8N4O2 requires; C, 52.94; H, 3.95; N, 27.44%).

1. customgave the free acid in quantitative yield
2. customRecrystallisation from water containing a minimum of ethanol
3. customgave material of mp 149.5-150.5° C. (dec) (lit. mp. 153° C.