Ethyl cyanoacetate → ethyl 5-amino-1-p-tolyl-1H-1,2,3-triazole-4-carboxylate

Participants

Reaction Steps

Reaction of p-tolyl azide (9.38 g; 0.0705 mole) with ethyl cyanoacetate (7.96 g: 0.0705 mole) as described in example 1a gave 12.76 g (74%) of the triazole of mp (EtOH) 152-153° C. (lit mp 147.5° C., B. R. Brown, D. L. Hammick and S. G. Heritage J. Chem. Soc. 3870 [1953]). (Found; C, 58.38; H 5.90; N, 22.89; C12H14N4O2 requires; C, 58.52; H, 5.73; N, 22.75%).

Provenance & Evidence