Sulfuric Acid → HCID 70156898, compound

Participants

Reaction Steps

A solution of 96% sulfuric acid (0.196 g) in isopropanol (2 ml) is added to a solution of 4-(4-chlorophenyl)-1,2,3,6-tetrahydro-1-[4-(1H-1,2,4-triazol-1-yl)butyl]pyridine (0.63 g, 2 mmol) in isopropanol (6 ml) cooled on an ice bath. After a few minutes a precipitate appears, which is filtered, washed with cold ethanol and dried, yielding 0.74 g (90%) of 4-(4-chlorophenyl)-1,2,3,6-tetrahydro-1-[4-(1H-1,2,4-triazol-1-yl)butyl]pyridine sulfate of m.p. 164-6° C.

Provenance & Evidence