Thiazolidine → HCID 18313779, compound

HRID 276982Notes

Reaction equation

HRID 276982 reaction equation
[C:1]([N:4]1[CH:8]([C:9]([OH:11])=[O:10])[CH2:7][S:6][CH:5]1[C:12]1[CH:17]=[C:16]([O:18][C:19](=[O:21])[CH3:20])[CH:15]=[CH:14][C:13]=1[OH:22])(=[O:3])[CH3:2].S1[CH2:27][CH2:26]NC1>>[CH2:26]([O:10][C:9]([CH:8]1[CH2:7][S:6][CH:5]([C:12]2[CH:17]=[C:16]([O:18][C:19](=[O:21])[CH3:20])[CH:15]=[CH:14][C:13]=2[OH:22])[N:4]1[C:1](=[O:3])[CH3:2])=[O:11])[CH3:27]

Participants

3

Reactant 2

HCID 10444ThiazolidineHCID 9927300HCID 9927300, compound

Product 1

HCID 18313779HCID 18313779, compound

Procedure

The procedure described above for the preparation of 3-acetyl-2-(2-hydroxy-5-acetyloxyphenyl)-1,3-thiazolidine-4-carboxylic acid (4) was followed to prepare 12, except an ethyl ester of the thiazolidine was employed as starting material.

Workup

  1. customto prepare 12

Sources & evidence

ORD record
ord-b4be83befe6c41babf765a173d4f8bc9
Source dataset
uspto-grants-2002_03
Patent number
US06355661B1

Reaction notes

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