3-Methyl-2-(naphthalen-2-yl)butanoic acid → Cyano[6-(4-fluorophenoxy)-2-pyridyl]methyl 2-(2-naphthyl)-3-methylbutanoate

HRID 27700Notes

Reaction equation

HRID 27700 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]([CH:15]([CH3:17])[CH3:16])[C:12]([OH:14])=[O:13].[C:18]([CH:20]([C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([O:28][C:29]2[CH:34]=[CH:33][C:32]([F:35])=[CH:31][CH:30]=2)[N:23]=1)O)#[N:19]>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]([CH:15]([CH3:17])[CH3:16])[C:12]([O:14][CH:20]([C:18]#[N:19])[C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([O:28][C:29]2[CH:34]=[CH:33][C:32]([F:35])=[CH:31][CH:30]=2)[N:23]=1)=[O:13]

Participants

3

Procedure

Following the procedure of Example 3, 2-(2-naphthyl)-3-methylbutanoic acid is reacted with cyano [6-(4-fluorophenoxy)-2-pyridyl]methanol to give cyano[6-(4-fluorophenoxy)-2-pyridyl]methyl 2-(2-naphthyl)-3-methylbutanoate.

Sources & evidence

ORD record
ord-7b9dd3bf44fd456684a08a009b438052
Source dataset
uspto-grants-1980_09
Patent number
US04223033

Reaction notes

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