3-Methyl-2-(naphthalen-2-yl)butanoic acid → [6-(4-Fluorophenoxy)-2-pyridyl]methyl 2-(2-naphthyl)-3methylbutanoate

HRID 27701Notes

Reaction equation

HRID 27701 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]([CH:15]([CH3:17])[CH3:16])[C:12]([OH:14])=[O:13].[F:18][C:19]1[CH:33]=[CH:32][C:22]([O:23][C:24]2[N:29]=[C:28]([CH2:30]O)[CH:27]=[CH:26][CH:25]=2)=[CH:21][CH:20]=1>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]([CH:15]([CH3:17])[CH3:16])[C:12]([O:14][CH2:30][C:28]1[CH:27]=[CH:26][CH:25]=[C:24]([O:23][C:22]2[CH:32]=[CH:33][C:19]([F:18])=[CH:20][CH:21]=2)[N:29]=1)=[O:13]

Participants

3

Reactant 2

HCID 139522283-Methyl-2-(naphthalen-2-yl)butanoic acidHCID 20285867[6-(4-Fluorophenoxy)-2-pyridyl]methanol

Product 1

HCID 23341823[6-(4-Fluorophenoxy)-2-pyridyl]methyl 2-(2-naphthyl)-3methylbutanoate

Procedure

The acid chloride of 2-(2-naphthyl)-3-methylbutanoic acid is reacted with [6-(4-fluorophenoxy)-2-pyridyl]methanol using the procedure of Example 1 to give [6-(4-fluorophenoxy)-2-pyridyl]methyl 2-(2-naphthyl)-3methylbutanoate.

Sources & evidence

ORD record
ord-8637a4b211ad4f9b8d59e7ea765fda78
Source dataset
uspto-grants-1980_09
Patent number
US04223033

Reaction notes

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