3-(2-Propyl-pyridin-4-yl)-acrylonitrile → 2-Furan-2-yl-7-(2-propyl-pyridin-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277021Notes

Reaction equation

HRID 277021 reaction equation
C1(S([CH2:10][C:11]2[N:15]=[C:14]([C:16]3[O:17][CH:18]=[CH:19][CH:20]=3)[NH:13][N:12]=2)(=O)=O)C=CC=CC=1.[CH2:21]([C:24]1[CH:29]=[C:28]([CH:30]=[CH:31][C:32]#[N:33])[CH:27]=[CH:26][N:25]=1)[CH2:22][CH3:23]>>[O:17]1[CH:18]=[CH:19][CH:20]=[C:16]1[C:14]1[N:15]=[C:11]2[CH:10]=[C:30]([C:28]3[CH:27]=[CH:26][N:25]=[C:24]([CH2:21][CH2:22][CH3:23])[CH:29]=3)[CH:31]=[C:32]([NH2:33])[N:12]2[N:13]=1

Participants

3

Reactant 2

HCID 700871883-(2-Propyl-pyridin-4-yl)-acrylonitrileHCID 178527402HCID 178527402, compound

Product 1

HCID 226297122-Furan-2-yl-7-(2-propyl-pyridin-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

Procedure

The title compound, MS m/e (%): 319 (M+, 100), was prepared in accordance with the general method of example 1 from 3-benzenesulfonylmethyl-5-furan-2-yl-1H-[1,2,4]triazole and 3-(2-propyl-pyridin-4-yl)-acrylonitrile.

Sources & evidence

ORD record
ord-949c0afa484c45749bbde86151ee3366
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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