反应详情

1.00, (0.003 mol) Thiophene-2-carboxylic acid N′-(2-benzenesulfonyl-1-imino-ethyl)-hydrazide were heated at 200° C. for 20 minutes. The molten mass Bras then cooled, dissolved in 5 ml hot ethanol and stirred for one hour at room temperature. The precipitated crystals were filtered off and dried to yield 0.87 g (93%) 3-benzenesulfonylmethyl-5-thiophen-2-yl-1H-[1,2,4]triazole as yellow crystals with mp. 191-193° C. MS m/e (%): 305 (M+, 100).

1. temperatureThe molten mass Bras then cooled
2. filtrationThe precipitated crystals were filtered off
3. customdried