Pyridine-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide → HCID 178527399, compound

HRID 277031Notes

Reaction equation

HRID 277031 reaction equation
[NH2:1][C:2](=[N:13][NH:14][C:15]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1)=O)[CH2:3][S:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)(=[O:6])=[O:5]>C(O)C>[C:7]1([S:4]([CH2:3][C:2]2[N:1]=[C:15]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=3)[NH:14][N:13]=2)(=[O:6])=[O:5])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

3

Reactant 1

HCID 86757847Pyridine-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide

Product 1

HCID 178527399HCID 178527399, compoundYield 84%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

7.70 g (0.025 mol) Pyridine-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide were heated at 200° C. for 20 minutes. The molten mass was then cooled, dissolved in 30 ml hot ethanol and stirred for two hous at room temperature. The precipitated crystals were filtered off and dried to yield 6.22 g (84%) 3-benzenesulfonylmethyl-5-pyridin-2-yl-1H-[1,2,4]triazole. MS m/e (%): 300 (M+, 100).

Workup

  1. temperatureThe molten mass was then cooled
  2. filtrationThe precipitated crystals were filtered off
  3. customdried

Sources & evidence

ORD record
ord-46c51b5e570049dc992379bbc547c901
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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