3-(3-Pyridinyl)-2-propenenitrile → 2-Phenyl-7-pyridin-3-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277035Notes

Reaction equation

HRID 277035 reaction equation
C1(S([CH2:10][C:11]2[N:15]=[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[NH:13][N:12]=2)(=O)=O)C=CC=CC=1.[N:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH:28]=[CH:29][C:30]#[N:31])[CH:23]=1>>[C:16]1([C:14]2[N:15]=[C:11]3[CH:10]=[C:28]([C:24]4[CH:23]=[N:22][CH:27]=[CH:26][CH:25]=4)[CH:29]=[C:30]([NH2:31])[N:12]3[N:13]=2)[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 537301363-(3-Pyridinyl)-2-propenenitrileHCID 1785273983-benzenesulfonylmethyl-5-phenyl-1H-[1,2,4]triazole

Product 1

HCID 183135622-Phenyl-7-pyridin-3-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

Procedure

The title compound, mp. 201-203° C., MS m/e (%): 288 (M+H+, 100), was prepared in accordance with the general method of example 22 from 3-benzenesulfonylmethyl-5-phenyl-1H-[1,2,4]triazole and 3-pyridin-3-yl-acrylonitrile.

Sources & evidence

ORD record
ord-6ca0b8e87c9b4bb1874803e11d19e5ba
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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