3-Furaldehyde → HCID 18313706, compound

HRID 277073Notes

Reaction equation

HRID 277073 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]=[C:4]([NH2:9])[CH:3]=1.C1(C)C=C(C)C=C(C)C=1S(O[NH2:22])(=O)=O.[O:24]1[CH:28]=[CH:27][C:26]([CH:29]=O)=[CH:25]1>>[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]2[N:22]=[C:29]([C:26]3[CH:27]=[CH:28][O:24][CH:25]=3)[N:9]=[C:4]2[CH:3]=1

Participants

4

Reactant 3

HCID 103513-FuraldehydeHCID 114353934-Bromo-2,6-diaminopyridineHCID 11830845O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine

Product 1

HCID 18313706HCID 18313706, compound

Procedure

The title compound, MS m/e (%): 281 (M++2, 100), was prepared in accordance with the general method of example 63 from 4-bromo-pyridine-2,6-diamine, O-mesitylene-sulfonylhydroxylamine, and 3-furaldehyde. The purification was performed with reversed phase HPLC eluting with an acetonitrile/water gradient.

Sources & evidence

ORD record
ord-da200a9475c34a8e8ce68bdca67bb90f
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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