3-Fluorobenzaldehyde → HCID 18313655, compound

HRID 277075Notes

Reaction equation

HRID 277075 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]=[C:4]([NH2:9])[CH:3]=1.C1(C)C=C(C)C=C(C)C=1S(O[NH2:22])(=O)=O.[F:24][C:25]1[CH:26]=[C:27]([CH:30]=[CH:31][CH:32]=1)[CH:28]=O>>[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]2[N:22]=[C:28]([C:27]3[CH:30]=[CH:31][CH:32]=[C:25]([F:24])[CH:26]=3)[N:9]=[C:4]2[CH:3]=1

Participants

4

Reactant 3

HCID 680093-FluorobenzaldehydeHCID 114353934-Bromo-2,6-diaminopyridineHCID 11830845O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine

Product 1

HCID 18313655HCID 18313655, compound

Procedure

The title compound, MS m/e (%): 307 (M+, 100), was prepared in accordance with the general method of example 63 from 4-bromo-pyridine-2,6-diamine, O-mesitylene-sulfonylhydroxylamine, and 3-fluoro-benzaldehyde. The purification was performed with reversed phase HPLC eluting with an acetonitrile/water gradient.

Sources & evidence

ORD record
ord-99ac9fe7b31a49eea74062aeb1293651
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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