4-Bromo-2,6-diaminopyridine → 7-Bromo-2-(6-methoxy-pyridin-2-yl)-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine
反応式
[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]=[C:4]([NH2:9])[CH:3]=1.C1(C)C=C(C)C=C(C)C=1S(O[NH2:22])(=O)=O.[CH3:24][O:25][C:26]1[N:31]=[C:30]([CH:32]=O)[CH:29]=[CH:28][CH:27]=1>>[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]2[N:22]=[C:32]([C:30]3[CH:29]=[CH:28][CH:27]=[C:26]([O:25][CH3:24])[N:31]=3)[N:9]=[C:4]2[CH:3]=1参加物
4
実験手順
The title compound, MS m/e (%): 320 (M+, 100), was prepared in accordance with the general method of example 63 from 4-bromo-pyridine-2,6-diamine, O-mesitylene-sulfonyl-hydroxylamine, and 6-methoxy-pyridine-2-carbaldehyde. The purification was performed with reversed phase HPLC eluting with an acetonitrile/water gradient.
出典と根拠
- ORDレコード
- ord-6bf6c39c11e54be2965f9512c6591c03
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06355653B1
反応ノート
読み込み中…