3-(5-Chloro-pyridin-2-yl)-acrylonitrile → 7-(5-Chloro-pyridin-2-yl)-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277097Notes

Reaction equation

HRID 277097 reaction equation
C1(S([CH2:10][C:11]2[N:15]=[C:14]([C:16]3[O:17][CH:18]=[CH:19][CH:20]=3)[NH:13][N:12]=2)(=O)=O)C=CC=CC=1.[Cl:21][C:22]1[CH:23]=[CH:24][C:25]([CH:28]=[CH:29][C:30]#[N:31])=[N:26][CH:27]=1>>[Cl:21][C:22]1[CH:23]=[CH:24][C:25]([C:28]2[CH:29]=[C:30]([NH2:31])[N:12]3[N:13]=[C:14]([C:16]4[O:17][CH:18]=[CH:19][CH:20]=4)[N:15]=[C:11]3[CH:10]=2)=[N:26][CH:27]=1

Participants

3

Reactant 2

HCID 700891653-(5-Chloro-pyridin-2-yl)-acrylonitrileHCID 178527402HCID 178527402, compound

Product 1

HCID 99048457-(5-Chloro-pyridin-2-yl)-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

Procedure

The title compound, MS m/e (%): 312 (M+H+, 100), was prepared in accordance with the general method of example 1 from 3-benzenesulfonylmethyl-5-furan-2-yl-1H-[1,2,4]triazole and 3-(5-chloro-pyridin-2-yl)-acrylonitrile.

Sources & evidence

ORD record
ord-141a8f54131c4339b53599c12b0d486d
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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