Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 277106Generated: October 31, 2026

(Z)-3-(6-methoxy-pyridin-3-yl)-acrylonitrile → 2-(2-Fluoro-phenyl)-7-(6-methoxy-pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

https://huagongshe.com/reaction/277106

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Z)-3-(6-methoxy-pyridin-3-yl)-acrylonitrileHCID 70088298—
Reactant3-benzenesulfonylmethyl-5-(2-fluoro-phenyl)-1H-[1,2,4]triazoleHCID 178527397—
Product2-(2-Fluoro-phenyl)-7-(6-methoxy-pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-5-ylamineHCID 22629682—

Reaction Steps

The title compound, MS m/e (%):336(M+H+,100), was prepared in accordance with the general method of example 1 from 3-benzenesulfonylmethyl-5-(2-fluoro-phenyl)-1H-[1,2,4]triazole and (E)/(Z)-3-(6-methoxy-pyridin-3-yl)-acrylonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06355653B1
Source datasetuspto-grants-2002_03
ORD IDord-cdf250fb76584672b04a2c9ab3452146
Source noteuspto-grants-2002_03