(Z)-3-(5-ethyl-pyridin-2-yl)-acrylonitrile → 7-(5-Ethyl-pyridin-2-yl)-2-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277109Notes

Reaction equation

HRID 277109 reaction equation
C1(S([CH2:10][C:11]2[N:12]=[C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)[NH:14][N:15]=2)(=O)=O)C=CC=CC=1.[CH2:22]([C:24]1[CH:25]=[CH:26][C:27](/[CH:30]=[CH:31]\[C:32]#[N:33])=[N:28][CH:29]=1)[CH3:23]>>[CH2:22]([C:24]1[CH:25]=[CH:26][C:27]([C:30]2[CH:31]=[C:32]([NH2:33])[N:15]3[N:14]=[C:13]([C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=4)[N:12]=[C:11]3[CH:10]=2)=[N:28][CH:29]=1)[CH3:23]

Participants

3

Reactant 2

HCID 86757852(Z)-3-(5-ethyl-pyridin-2-yl)-acrylonitrileHCID 178527399HCID 178527399, compound

Product 1

HCID 99269407-(5-Ethyl-pyridin-2-yl)-2-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

Procedure

The title compound, MS m/e (%):317 (M+H+,100), was prepared in accordance with the general method of example 1 from 2-(5-benzenesulfonylmethyl-2H-[1,2,4]triazol-3-yl)-pyridine and (E)/(Z)-3-(5-ethyl-pyridin-2-yl)-acrylonitrile.

Sources & evidence

ORD record
ord-3a927598a5144673b438f823123710d8
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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