(Z)-3-pyridin-2-yl-acrylonitrile → 2,7-Di-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277110Notes

Reaction equation

HRID 277110 reaction equation
C1(S([CH2:10][C:11]2[N:12]=[C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)[NH:14][N:15]=2)(=O)=O)C=CC=CC=1.[N:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1/[CH:28]=[CH:29]\[C:30]#[N:31]>>[N:17]1[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=1[C:13]1[N:12]=[C:11]2[CH:10]=[C:28]([C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][N:22]=3)[CH:29]=[C:30]([NH2:31])[N:15]2[N:14]=1

Participants

3

Reactant 2

HCID 45116217(Z)-3-pyridin-2-yl-acrylonitrileHCID 178527399HCID 178527399, compound

Product 1

HCID 98607322,7-Di-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

Procedure

The title compound, MS m/e (%):289 (M+H+,100), was prepared in accordance with the general method of example 1 from 2-(5-benzenesulfonylmethyl-2H-[1,2,4]triazol-3-yl)-pyridine and (E)/(Z)-3-pyridin-2-yl-acrylonitrile.

Sources & evidence

ORD record
ord-316f11fddb374af793b09a1c08392d83
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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