(Z)-3-pyridin-2-yl-acrylonitrile → 2-Methylsulfanyl-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277120Notes

Reaction equation

HRID 277120 reaction equation
C1(S([CH2:10][C:11]2[N:15]=[C:14]([S:16][CH3:17])[NH:13][N:12]=2)(=O)=O)C=CC=CC=1.[N:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1/[CH:24]=[CH:25]\[C:26]#[N:27]>>[CH3:17][S:16][C:14]1[N:15]=[C:11]2[CH:10]=[C:24]([C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][N:18]=3)[CH:25]=[C:26]([NH2:27])[N:12]2[N:13]=1

Participants

3

Reactant 2

HCID 45116217(Z)-3-pyridin-2-yl-acrylonitrileHCID 178503479HCID 178503479, compound

Product 1

HCID 183136312-Methylsulfanyl-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

Procedure

The title compound, MS m/e (%):258 (M+H+,100), was prepared in accordance with the general method of example 1 from 3-benzenesulfonylmethyl-5-methylsulfanyl-1H-[1,2,4]triazole and (E)/(Z)-3-pyridin-2-yl-acrylonitrile.

Sources & evidence

ORD record
ord-3f2c5b0dac9e4e27a2326d4870984f5e
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

Loading…