HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,8-Diazabicyclo(5.4.0)undec-7-ene → 2-(2-Methyl-imidazol-1-yl)-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 2-Methanesulfinyl-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine | HCID 22629703 | — |
| Solvent | 2-Methylimidazole | HCID 12749 | — |
| Product | 2-(2-Methyl-imidazol-1-yl)-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine | HCID 18313660 | — |
Reaction Steps
The title compound, MS m/e (%):292 (M+H+,100), was prepared in accordance with the method of example 339b) from 2-methanesulfinyl-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine and 1,8-diazabicyclo[5.4.0]undec-7-en in 2-methylimidazole at 170° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06355653B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-6bfe6746b57c4ed5bae45fa92cce01fc |
| Source note | uspto-grants-2002_03 |