Pyridine → HCID 178527709, compound

HRID 27715Notes

Reaction equation

HRID 27715 reaction equation
Br.[NH:2]1[C:6]([C:7]2[C:15](=N)[N:14]3[C:10]([S:11][C:12]4[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=43)=[N:9][CH:8]=2)=[N:5][N:4]=[N:3]1.P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:22].N1C=CC=CC=1>O>[NH:2]1[C:6]([C:7]2[C:15](=[S:22])[N:14]3[C:10]([S:11][C:12]4[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=43)=[N:9][CH:8]=2)=[N:5][N:4]=[N:3]1

Participants

5

Reactant 3

HCID 1049PyridineHCID 14817Phosphorus sulfide (P2S5)HCID 178419686HCID 178419686, compound

Product 1

HCID 178527709HCID 178527709, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

- The product of Example 24, 0.02 mole, and 12.0 g. (0.054 mole) of P2S5 in 125 ml. of pyridine is heated at reflux for 5 hrs. and then poured into 1 l. of ice and water mixture. The product is collected by filtration, the solid dissolved in dilute NaOH, treated with decolorizing carbon, filtered and the filtrate acidified whereupon the purified product precipitated and was collected on a filter.

Workup

  1. temperatureat reflux for 5 hrs
  2. additionand then poured into 1 l
  3. filtrationThe product is collected by filtration
  4. dissolutionthe solid dissolved in dilute NaOH
  5. additiontreated with decolorizing carbon
  6. filtrationfiltered
  7. customprecipitated
  8. customwas collected on a filter

Sources & evidence

ORD record
ord-6ae042acd895424b920eba5232aba34b
Source dataset
uspto-grants-1980_09
Patent number
US04223031

Reaction notes

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