HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → HCID 18682354, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Propanedioic acid, monoethyl ester | HCID 3595298 | — |
| Reactant | 5-Isoxazolecarboxylic acid, 3-[1-[[(1,1-dimethylethoxy)carbonyl]amino]-3-methylbutyl]- | HCID 18313937 | — |
| Product | HCID 18682354 | HCID 18682354 | — |
Reaction Steps
The title compound was prepared from 3-(1-tert-butoxycarbonylamino-3-methyl-butyl)-isoxazole-5-carboxylic acid by treatment with carbonyldiimidazole followed by the magnesium salt of mono-ethyl malonate as described in Angew. Chem. Int Ed. Eng., 18 (1979), p. 72.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06355662B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-4daf30eda7f8429cb4c9bdc2be046842 |
| Source note | uspto-grants-2002_03 |