2-Bromophenylacetic acid → HCID 18546324, compound

HRID 277244Notes

Reaction equation

HRID 277244 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:18]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:20]=1)[NH2:17]>>[CH3:12][O:13][C:14]1[CH:15]=[C:16]([NH:17][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:18]=[C:19]([C:21]([F:22])([F:24])[F:23])[CH:20]=1

Participants

3

Reactant 2

HCID 877542-Bromophenylacetic acidHCID 6056715-(Trifluoromethyl)-m-anisidine

Product 1

HCID 18546324HCID 18546324, compound

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3-methoxy-5-(trifluoromethyl)aniline to yield 2-[(3-methoxy-5-(trifluoromethyl)phenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-2c9baa507dc2472c8f9e0bc488f41936
Source dataset
uspto-grants-2002_03
Patent number
US06355680B1

Reaction notes

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