2-Fluoroaniline → HCID 18546352, compound

HRID 277251Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[CH:19]=[CH:18][CH:17]=[CH:16][C:14]=1[NH2:15]>>[F:12][C:13]1[CH:19]=[CH:18][CH:17]=[CH:16][C:14]=1[NH:15][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]

Participants

Reactant 2

HCID 95842-Fluoroaniline

HCID 877542-Bromophenylacetic acid

Product 1

HCID 18546352HCID 18546352, compound

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 2-fluoroaniline to yield 2-[(2-fluorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record: ord-2b63cbcb702e4a5490385cf42793fc90
Source dataset: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06355680B1

Reaction notes

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