4-Fluoroaniline → HCID 18546354, compound

HRID 277253Notes

Reaction equation

HRID 277253 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[CH:15][CH:14]=1>>[F:12][C:13]1[CH:19]=[CH:18][C:16]([NH:17][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])=[CH:15][CH:14]=1

Participants

3

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 4-fluoroaniline to yield 2-[(4-fluorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-883daa527b7448a992f3cd2799734ae9
Source dataset
uspto-grants-2002_03
Patent number
US06355680B1

Reaction notes

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