3,4-Difluoroaniline → HCID 18546337, compound

HRID 277260Notes

Reaction equation

HRID 277260 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][C:19]=1[F:20])[NH2:16]>>[F:12][C:13]1[CH:14]=[C:15]([NH:16][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:17]=[CH:18][C:19]=1[F:20]

Participants

3

Reactant 2

HCID 774693,4-DifluoroanilineHCID 877542-Bromophenylacetic acid

Product 1

HCID 18546337HCID 18546337, compound

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3,4-difluoroaniline to yield 2-[(3,4-difluorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-a8399848501f4cb2b8ab13fe1df32320
Source dataset
uspto-grants-2002_03
Patent number
US06355680B1

Reaction notes

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