2-Bromophenylacetic acid → HCID 18546368, compound

HRID 277261Notes

Reaction equation

HRID 277261 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([F:20])[CH:19]=1)[NH2:16]>>[F:12][C:13]1[CH:14]=[C:15]([NH:16][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:17]=[C:18]([F:20])[CH:19]=1

Participants

3

Reactant 2

HCID 877542-Bromophenylacetic acidHCID 965953,5-Difluoroaniline

Product 1

HCID 18546368HCID 18546368, compound

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3,5-difluoroaniline to yield 2-[(3,5-difluorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-b29d02a55b6243cf9a9e9c5f51ba60bc
Source dataset
uspto-grants-2002_03
Patent number
US06355680B1

Reaction notes

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