4-Fluoro-3-nitroaniline → HCID 18546400, compound

HRID 277271Notes

Reaction equation

HRID 277271 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[N+:12]([C:15]1[CH:16]=[C:17]([CH:19]=[CH:20][C:21]=1[F:22])[NH2:18])([O-:14])=[O:13]>>[N+:12]([C:15]1[CH:16]=[C:17]([NH:18][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:19]=[CH:20][C:21]=1[F:22])([O-:14])=[O:13]

Participants

3

Reactant 2

HCID 677684-Fluoro-3-nitroanilineHCID 877542-Bromophenylacetic acid

Product 1

HCID 18546400HCID 18546400, compound

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3-nitro-4-fluoroaniline to yield 2-[(3-nitro-4-fluorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-0f17ba7b57984859a02704eb5b80d415
Source dataset
uspto-grants-2002_03
Patent number
US06355680B1

Reaction notes

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