2-Bromophenylacetic acid → HCID 18546417, compound
Reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[CH:19]=[C:18]([Br:20])[CH:17]=[CH:16][C:14]=1[NH2:15]>>[F:12][C:13]1[CH:19]=[C:18]([Br:20])[CH:17]=[CH:16][C:14]=1[NH:15][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]Participants
3
Procedure
In the manner described in example 3, 2-bromophenylacetic acid is condensed with 2-fluoro-4-bromoaniline to yield 2-[(2-fluoro-4-bromophenyl)amino]phenylacetic acid.
Sources & evidence
- ORD record
- ord-ac376d4285d44c5092674b467cd0b308
- Source dataset
- uspto-grants-2002_03
- Patent number
- US06355680B1
Reaction notes
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