4-Methyl-3-nitroaniline → HCID 18546365, compound
Reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[N+:12]([C:15]1[CH:16]=[C:17]([CH:19]=[CH:20][C:21]=1[CH3:22])[NH2:18])([O-:14])=[O:13]>>[N+:12]([C:15]1[CH:16]=[C:17]([NH:18][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:19]=[CH:20][C:21]=1[CH3:22])([O-:14])=[O:13]Participants
3
Procedure
In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3-nitro-4-methylaniline to yield 2-[(3-nitro-4-methylphenyl)amino]phenylacetic acid.
Sources & evidence
- ORD record
- ord-3eca989ffc814fe996516f92d703b2f9
- Source dataset
- uspto-grants-2002_03
- Patent number
- US06355680B1
Reaction notes
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