4-Propylaniline → 2-[(4-Propylphenyl)amino]phenylacetic acid

HRID 277285Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[CH2:12]([C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=1)[CH2:13][CH3:14]>>[CH2:12]([C:15]1[CH:21]=[CH:20][C:18]([NH:19][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])=[CH:17][CH:16]=1)[CH2:13][CH3:14]

Participants

Reactant 2

HCID 759084-Propylaniline

HCID 877542-Bromophenylacetic acid

Product 1

HCID 185463902-[(4-Propylphenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 4-propylaniline to yield 2-[(4-propylphenyl)amino]phenylacetic acid.

Sources & evidence

ORD record: ord-aa094b2850da4a85a0fd3f5680bc0e55
Source dataset: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06355680B1

Reaction notes

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