3,4,5-Trimethoxyaniline → HCID 18546349, compound

HRID 277287Notes

Reaction equation

HRID 277287 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:18]=[C:19]([O:23][CH3:24])[C:20]=1[O:21][CH3:22])[NH2:17]>>[CH3:24][O:23][C:19]1[CH:18]=[C:16]([NH:17][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:15]=[C:14]([O:13][CH3:12])[C:20]=1[O:21][CH3:22]

Participants

3

Reactant 2

HCID 322853,4,5-TrimethoxyanilineHCID 877542-Bromophenylacetic acid

Product 1

HCID 18546349HCID 18546349, compound

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3,4,5-trimethoxyaniline to yield 2-[(3,4,5-trimethoxyphenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-86dd2413e6714ddf8cc56a1a0daa9f14
Source dataset
uspto-grants-2002_03
Patent number
US06355680B1

Reaction notes

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