4-Butylaniline → 2-[(4-Butylphenyl)amino]phenylacetic acid

HRID 277288Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[CH2:12]([C:16]1[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][CH:17]=1)[CH2:13][CH2:14][CH3:15]>>[CH2:12]([C:16]1[CH:17]=[CH:18][C:19]([NH:20][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])=[CH:21][CH:22]=1)[CH2:13][CH2:14][CH3:15]

Participants

Reactant 2

HCID 76944-Butylaniline

HCID 877542-Bromophenylacetic acid

Product 1

HCID 185463402-[(4-Butylphenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 4-butylaniline to yield 2-[(4-butylphenyl)amino]phenylacetic acid.

Sources & evidence

ORD record: ord-9f1f6c92cfc44fe590a05e1e99f46521
Source dataset: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06355680B1

Reaction notes

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