2,2,6-Trimethyl-4H-1,3-dioxin-4-one → HCID 53816887, compound

HRID 277305Notes

Reaction equation

HRID 277305 reaction equation
[CH3:1][C:2]1([CH3:16])[CH2:7][CH:6]([O:8][C:9](=[O:13])[CH:10]([CH3:12])[OH:11])[CH2:5][C:4]([CH3:15])([CH3:14])[NH:3]1.CC1(C)[O:23][C:22](=O)[CH:21]=[C:20]([CH3:25])[O:19]1>C1(C)C=CC=CC=1>[CH3:16][C:2]1([CH3:1])[CH2:7][CH:6]([O:8][C:9](=[O:13])[CH:10]([O:11][C:22](=[O:23])[CH2:21][C:20]([CH3:25])=[O:19])[CH3:12])[CH2:5][C:4]([CH3:15])([CH3:14])[NH:3]1

Participants

4

Reactant 2

HCID 793682,2,6-Trimethyl-4H-1,3-dioxin-4-oneHCID 70169616HCID 70169616, compound

Product 1

HCID 53816887HCID 53816887, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Lactic acid 2,2,6,6-tetramethyl-4-piperidyl ester (5 g, 21.8 mmol) was dissolved in 100 ml of toluene. At reflux temperature, 3.1 g (21.8 mmol) of 2,2,6-trimethyl-4H-1,3-dioxine-4-one was added dropwise. After 3 hours at reflux, the solvent was distilled of in vacuo. A viscous residue was left. Yield 4.8 g (70%).

Workup

  1. additionwas added dropwise
  2. temperatureAfter 3 hours at reflux
  3. distillationthe solvent was distilled of in vacuo
  4. waitA viscous residue was left

Sources & evidence

ORD record
ord-4434d5bd0ecb449a9087ba52618abfbf
Source dataset
uspto-grants-2002_03
Patent number
US06355713B1

Reaction notes

Loading…