2,6-Di-tert-butylphenol → 2,6-DI-Tert-butyl-cyclohexanone

HRID 277318Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 277318
[C:1]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:6]=1[OH:15])([CH3:4])([CH3:3])[CH3:2]>CO.[Rh]>[C:11]([CH:7]1[CH2:8][CH2:9][CH2:10][CH:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[C:6]1=[O:15])([CH3:14])([CH3:13])[CH3:12]

Komponenten

4

Edukt 1

HCID 314052,6-Di-tert-butylphenol

Produkt 1

HCID 2289732,6-DI-Tert-butyl-cyclohexanoneAusbeute 97 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23948RhodiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

500.0 g of 2,6-di-tert-butyl-phenol are hydrogenated in 1200 ml of methanol under 100 bar at 60° C. using 50 g of rhodium on carbon (5%) for 12 hours. The catalyst is filtered off and washed with ethanol. The solvent is distilled off under reduced pressure and the residue is distilled under high vacuum to leave 494.3 g (97% of theory) of 2,6-di-tert-butyl-cyclohexanone as a mixture of colourless crystals with a colourless liquid. Boiling point of the isomers: 63° C. (0.1 mbar) and 67° C. (0.08 mbar). These products are converted into 2,6-di-tert-butyl-cyclohexanol as in Example A1.

Aufarbeitung

  1. customfor 12 hours
  2. filtrationThe catalyst is filtered off
  3. washwashed with ethanol
  4. distillationThe solvent is distilled off under reduced pressure
  5. distillationthe residue is distilled under high vacuum

Quellen und Nachweise

ORD-Eintrag
ord-bbd4ac6162a24133bf6b665fd3d0bc22
Quelldatensatz
uspto-grants-2002_03
Patentnummer
US06355783B1

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