反应详情

A mixture of 5-amino-3-(6-methoxy-m-tolyl)-1,2-benzisoxazole (8.40 g, 0.033 mol), 2-dimethylamino-4-(trifluoromethyl)-6H-1,3-oxazin-6-one (7.60 g, 0.036 mol), and acetic acid is refluxed for three hours, cooled, poured onto ice, and diluted with water. The resultant aqueous mixture is filtered to obtain a solid. The solid is washed with water and dried to give the title product as a pink solid which is identified by NMR spectral analyses.

1. temperatureis refluxed for three hours
2. temperaturecooled
3. additionpoured onto ice
4. filtrationThe resultant aqueous mixture is filtered
5. customto obtain a solid
6. washThe solid is washed with water
7. customdried